Lee RE: SARS Coronavirus Appears to be an FcgammaR Agent, Causing an Hyperimmune Response via a CD13 pathway - Implication for Therapeutic Interventions. JOIMR 2003;1:2
Figure 4: SARS E2-spike protein multiple sequence alignment to other human coronavirus E2-spike proteins
(SARS
E2-spike
proteins in bold).
CLUSTAL W (1.82) multiple sequence alignment
gi|29836496|ref|NP_828851.1| -MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYP---DEI 46
gi|30023954|gb|AAP13567.1| -MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYP---DEI 46
gi|476485|pir||JQ2168 MFLILLISLPTAFAVIGDLKCTSDNINDKDTGPPPISTDTVDVTNGLGTY 50
gi|306156|gb|AAA03055.1| MFLILLISLPTAFAVIGDLKCTSDNINDKDTGPPPISTDTVDVTNGLGTY 50
gi|549302|sp|P36334|VGL2_CVHOC MFLILLISLPTAFAVIGDLKCTSDNINDKDTGPPPISTDTVDVTNGLGTY 50
gi|138175|sp|P15423|VGL2_CVH22 ---MFVLLVAYALLHIAGCQTTNGLNTSYSVCNGCVGYSENVFAVESGGY 47
gi|1869755|emb|CAA71056.1| --------------------------------------------------
gi|29836496|ref|NP_828851.1| FRSDTLYLTQDLFLPFYSNVTGFHTINHTFGN-----------PVIPFKD 85
gi|30023954|gb|AAP13567.1| FRSDTLYLTQDLFLPFYSNVTGFHTINHTFDN-----------PVIPFKD 85
gi|476485|pir||JQ2168 YVLDRVYLNTTLFLNGYYPTSGSTYRNMALKGSVLLSRLWFKPPFLSDFI 100
gi|306156|gb|AAA03055.1| YVLDRVYLNTTLFLNGYYPTSGSTYRNMALKGSVLLSRLWFKPPFLSDFI 100
gi|549302|sp|P36334|VGL2_CVHOC YVLDRVYLNTTLFLNGYYPTSGSTYRNMALKGSVLLSRLWFKPPFLSDFI 100
gi|138175|sp|P15423|VGL2_CVH22 IPSDFAFNNWFLLTNTSSVVDGVVRS------------------FQPLLL 79
gi|1869755|emb|CAA71056.1| --------------------------------------------------
gi|29836496|ref|NP_828851.1| GIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIR---ACNFEL 132
gi|30023954|gb|AAP13567.1| GIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIR---ACNFEL 132
gi|476485|pir||JQ2168 NGIFAKVKNTKVIKDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQD 150
gi|306156|gb|AAA03055.1| NGIFAKVKNTKVIKDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQD 150
gi|549302|sp|P36334|VGL2_CVHOC NGIFAKVKNTKVIKDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQD 150
gi|138175|sp|P15423|VGL2_CVH22 NCLWSVSGLR--FTTGFVYFNGTGRGDCKGFSSDVLSDVIR----YNLNF 123
gi|1869755|emb|CAA71056.1| --------------------NGTGRGDCKGFSSDVLSDVIR----YNLNF 26
: . . *:: . :
gi|29836496|ref|NP_828851.1| CDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHL 182
gi|30023954|gb|AAP13567.1| CDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHL 182
gi|476485|pir||JQ2168 GDNKLQGLLEVSVCQYNMCEYPQTICHPNLGNHRKELWHLDTGVVSCLYK 200
gi|306156|gb|AAA03055.1| GDNKLQGLLEVSVCQYNMCEYPQTICHPNLGNHRKELWHLDTGVVSCLYK 200
gi|549302|sp|P36334|VGL2_CVHOC GDNKLQGLLEVSVCQYNMCEYPQTICHPNLGNHRKELWHLDTGVVSCLYK 200
gi|138175|sp|P15423|VGL2_CVH22 EEN----LRRGTILFKTSYGVVVFYCTNNTLVSGDAHIPFGTVLGNFYCF 169
gi|1869755|emb|CAA71056.1| EEN----LRRGTILFKTSYGVVVFYCTNNTLVSGDAHIPFGTVLGNFYCF 72
:* : . .. .
gi|29836496|ref|NP_828851.1| REFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLG-INITNF 231
gi|30023954|gb|AAP13567.1| REFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLG-INITNF 231
gi|476485|pir||JQ2168 RNFTYDVNADYLYFHFYQEGGTFYAYFTDTGVVTKFLFNVYLG-MALSHY 249
gi|306156|gb|AAA03055.1| RNFTYDVNADYLYFHFYQEGGTFYAYFTDTGVVTKFLFNVYLG-MALSHY 249
gi|549302|sp|P36334|VGL2_CVHOC RNFTYDVNADYLYFHFYQEGGTFYAYFTDTGVVTKFLFNVYLG-MALSHY 249
gi|138175|sp|P15423|VGL2_CVH22 VNTTIGNETTSAFVGALPKTVREFVISRTGHFYINGYRYFTLGNVEAVNF 219
gi|1869755|emb|CAA71056.1| VNTTIGNETTSAFVGALPKTVREFVISRTGHFYINGYRYFTLGNVEAVNF 122
: . : :. : : . ** : ::
gi|29836496|ref|NP_828851.1| RAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQN 281
gi|30023954|gb|AAP13567.1| RAILTAFSPAQDTWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQN 281
gi|476485|pir||JQ2168 YVMPLTCN------SKLTLEYWVTPLTSRQYLLAFNQDGIIFNAEDCMSD 293
gi|306156|gb|AAA03055.1| YVMPLTCN------SKLTLEYWVTPLTSRQYLLAFNQDGIIFNAEDCMSD 293
gi|549302|sp|P36334|VGL2_CVHOC YVMPLTCN------SKLTLEYWVTPLTSRQYLLAFNQDGIIFNAEDCMSD 293
gi|138175|sp|P15423|VGL2_CVH22 NVT-----------TAETTDFCTVALASYADVLVNVSQTSIANIIYCN-S 257
gi|1869755|emb|CAA71056.1| NVT-----------TAETTDFFTVALASYADVLVNVSQTSIANIIYCN-S 160
. : : . * . :* .: * : * .
gi|29836496|ref|NP_828851.1| PLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNA 331
gi|30023954|gb|AAP13567.1| PLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNA 331
gi|476485|pir||JQ2168 FMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLND 343
gi|306156|gb|AAA03055.1| FMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLND 343
gi|549302|sp|P36334|VGL2_CVHOC FMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLND 343
gi|138175|sp|P15423|VGL2_CVH22 VINRLRCDQLSFDVPDGFYSTSPIQSVELP--------VSIVSLPVYHKH 299
gi|1869755|emb|CAA71056.1| VINRLRCDQLSFDVPDGFYSTSPIQSVELP--------VSIVSLPVYHKH 202
: .::*. *: *.*. . : :
gi|29836496|ref|NP_828851.1| TKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSN 381
gi|30023954|gb|AAP13567.1| TKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSN 381
gi|476485|pir||JQ2168 KSVPSPLNWERKTFSNCNFNMSSLMSFIQADSFTCNNIDAAKIYGMCFSS 393
gi|306156|gb|AAA03055.1| KSVPSPLNWERKTFSNCNFNMSSLMSFIQADSFTCNNIDAAKIYGMCFSS 393
gi|549302|sp|P36334|VGL2_CVHOC KSVPSPLNWERKTFSNCNFNMSSLMSFIQADSFTCNNIDAAKIYGMCFSS 393
gi|138175|sp|P15423|VGL2_CVH22 TFIVLYVDFKPQSGGGKCFNCYPAGVNITLANFNET-KGPLCVDTSHFTT 348
gi|1869755|emb|CAA71056.1| TFIVLYVDFKPQSGGGKCFNCYPAGVNITLANFNET-KGPLCVDTSHFTT 251
. . :: :. .. : .*. .. : *:.
gi|29836496|ref|NP_828851.1| VYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDAT 431
gi|30023954|gb|AAP13567.1| VYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDAT 431
gi|476485|pir||JQ2168 ITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 443
gi|306156|gb|AAA03055.1| ITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 443
gi|549302|sp|P36334|VGL2_CVHOC ITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 443
gi|138175|sp|P15423|VGL2_CVH22 KYVAVYANVGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAM 398
gi|1869755|emb|CAA71056.1| KYVAVYANVGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAM 301
:. . .: *: . .: * : .
gi|29836496|ref|NP_828851.1| STGN----YNYKYRYLRHGKLRPFER-DISNVPFSPDGKPCTPPALNCYW 476
gi|30023954|gb|AAP13567.1| STGN----YNYKYRYLRHGKLRPFER-DISNVPFSPDGKPCTPPALNCYW 476
gi|476485|pir||JQ2168 VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPC 493
gi|306156|gb|AAA03055.1| VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPC 493
gi|549302|sp|P36334|VGL2_CVHOC VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPC 493
gi|138175|sp|P15423|VGL2_CVH22 PIVAN---WAYSKYYTIGSLYVSWSD------------------------ 421
gi|1869755|emb|CAA71056.1| PIVAN---WAYSKYYTIGSLYVSWSD------------------------ 324
: : . .
gi|29836496|ref|NP_828851.1| PLN----DYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGP--------- 513
gi|30023954|gb|AAP13567.1| PLN----DYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGP--------- 513
gi|476485|pir||JQ2168 KLNGSCVGSGPGKNNGIGTCPAGTNYLTCDNLCTPDPITFTGTYKCPQTK 543
gi|306156|gb|AAA03055.1| KLNGSCVGSGPGKNNGIGTCPAGTNYLTCDNLCTPDPITFTGTYKCPQTK 543
gi|549302|sp|P36334|VGL2_CVHOC KLNGSCVGSGPGKNNGIGTCPAGTNYLTCDNLCTPDPITFTGTYKCPQTK 543
gi|138175|sp|P15423|VGL2_CVH22 -------------GDGITGVPQPVEGVS---------------------- 436
gi|1869755|emb|CAA71056.1| -------------GDGITGVPQPVEGVS---------------------- 339
** * . ::
gi|29836496|ref|NP_828851.1| --------------------------------------------------
gi|30023954|gb|AAP13567.1| --------------------------------------------------
gi|476485|pir||JQ2168 SLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFAN 593
gi|306156|gb|AAA03055.1| SLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFAN 593
gi|549302|sp|P36334|VGL2_CVHOC SLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFAN 593
gi|138175|sp|P15423|VGL2_CVH22 --------------------------------------------------
gi|1869755|emb|CAA71056.1| --------------------------------------------------
gi|29836496|ref|NP_828851.1| -----------------KLSTDLIKNQCVNFNFNGLTGTGVLTPS-SKRF 545
gi|30023954|gb|AAP13567.1| -----------------KLSTDLIKNQCVNFNFNGLTGTGVLTPS-SKRF 545
gi|476485|pir||JQ2168 FILHDVNSGLTCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYY 643
gi|306156|gb|AAA03055.1| FILHDVNSGLTCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYY 643
gi|549302|sp|P36334|VGL2_CVHOC FILHDVNSGLTCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYY 643
gi|138175|sp|P15423|VGL2_CVH22 ------------------SFMNVTLDKCTKYNIYDVSGVGVIRVSNDTFL 468
gi|1869755|emb|CAA71056.1| ------------------SFMNVTLDKCTKYNIYDVSGVGVIRVSNDTFL 371
:: . *.:::: .: * *:: .
gi|29836496|ref|NP_828851.1| QPFQQFGRDVSDFTDSVRDPKTSEILDISPCAFGGVSVITPGTNASSEVA 595
gi|30023954|gb|AAP13567.1| QPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVA 595
gi|476485|pir||JQ2168 NSWQNLLYDSNGNLYGFRDYIINRTFMIRSCYSGRVSAAFHAN--SSEPA 691
gi|306156|gb|AAA03055.1| NSWQNLLYDSNGNLYGFRDYIINRTFMIRSCYSGRVSAAFHAN--SSEPA 691
gi|549302|sp|P36334|VGL2_CVHOC NSWQNLLYDSNGNLYGFRDYIINRTFMIRSCYSGRVSAAFHAN--SSEPA 691
gi|138175|sp|P15423|VGL2_CVH22 N--GITYTSTSGNLLGFKDVTKGTIYSITPCNPPDQLVVYQQAVVGAMLS 516
gi|1869755|emb|CAA71056.1| N--GITYTSTSGNLLGFKDVTKGTIYSITPCNPPDQLVVYQQAVVGAMLS 419
: . .. ..:* . * .* . .: :
gi|29836496|ref|NP_828851.1| VLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTS 645
gi|30023954|gb|AAP13567.1| VLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTS 645
gi|476485|pir||JQ2168 LLFRNIKCNYVFNNSLTRQLQPIN--------YFDSYLGCVVNAYNSTAI 733
gi|306156|gb|AAA03055.1| LLFRNIKCNYVFNNSLTRQLQPIN--------YFDSYLGCVVNAYNSTAI 733
gi|549302|sp|P36334|VGL2_CVHOC LLFRNIKCNYVFNNSLTRQLQPIN--------YFDSYLGCVVNAYNSTAI 733
gi|138175|sp|P15423|VGL2_CVH22 ENFTSYGFSNVVELPK----------------FFYASNGTYN-------- 542
gi|1869755|emb|CAA71056.1| ENFTSYGFSNVVELPK----------------FFYASNGTYN-------- 445
: . . * * : *
gi|29836496|ref|NP_828851.1| --YECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNN- 692
gi|30023954|gb|AAP13567.1| --YECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNN- 692
gi|476485|pir||JQ2168 SVQTCDLTVGSGYCVDYSKNRRSRGAITTGYRFTNFEPFTVNSVNDSLEP 783
gi|306156|gb|AAA03055.1| SVQTCDLTVGSGYCVDYSKNRRSRGAITTGYRFTNFEPFTVNSVNDSLEP 783
gi|549302|sp|P36334|VGL2_CVHOC SVQTCDLTVGSGYCVDYSKNRRSRGAITTGYRFTNFEPFTVNSVNDSLEP 783
gi|138175|sp|P15423|VGL2_CVH22 ---------CTDAVLTYSSFGVCADGSIIAVQPRNVSYDSVSAIVTANLS 583
gi|1869755|emb|CAA71056.1| ---------CTDAVLTYSSFGVCADGSIIAVQPRNVSYDSVSAIVTANLS 486
:. * . . . ... : .:: :
gi|29836496|ref|NP_828851.1| -----TIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQ 737
gi|30023954|gb|AAP13567.1| -----TIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQ 737
gi|476485|pir||JQ2168 VGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACKSQLVE 833
gi|306156|gb|AAA03055.1| VGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACKSQLVE 833
gi|549302|sp|P36334|VGL2_CVHOC VGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACKSQLVE 833
gi|138175|sp|P15423|VGL2_CVH22 --------IPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQ 625
gi|1869755|emb|CAA71056.1| --------IPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQ 528
**:::: . .* : : . :** ::*.. . * . * :
gi|29836496|ref|NP_828851.1| YGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGG------ 781
gi|30023954|gb|AAP13567.1| YGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGG------ 781
gi|476485|pir||JQ2168 YGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDD 883
gi|306156|gb|AAA03055.1| YGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDD 883
gi|549302|sp|P36334|VGL2_CVHOC YGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDD 883
gi|138175|sp|P15423|VGL2_CVH22 YTSACKTIEDALRNSARLESADVSEMLTFDKKAFTLANVSSFGD------ 669
gi|1869755|emb|CAA71056.1| YTSACKTIEDALRNSARLESADVSEMLTFDKKAFTLANVSSFGD------ 572
* * * :: * . :: : . .. *
gi|29836496|ref|NP_828851.1| FNFSQILPDP----LKPTKRSFIEDLLFNKVTLADAG-FMKQYGECLGDI 826
gi|30023954|gb|AAP13567.1| FNFSQILPDP----LKPTKRSFIEDLLFNKVTLADAG-FMKQYGECLGDI 826
gi|476485|pir||JQ2168 INFSPVLGCLGSECSKASSRSAIEDLLFDKVKLSDVG-FVEAYNNCTGGA 932
gi|306156|gb|AAA03055.1| INFSPVLGCLGSECSKASSRSAIEDLLFDKVKLSDVG-FVEAYNNCTGGA 932
gi|549302|sp|P36334|VGL2_CVHOC INFSPVLGCLGSECSKASSRSAIEDLLFDKVKLSDVG-FVEAYNNCTGGA 932
gi|138175|sp|P15423|VGL2_CVH22 YNLSSVIPSLPTSGSRVAGRSAIEDILFSKLVTSGLGTVDADYKKCTKGL 719
gi|1869755|emb|CAA71056.1| YNLSSVIPSLPTSGSRVAGRSAIEDILFSKLVTSGLGTVDADYKKCTKGL 622
*:* :: : : ** ***:**.*: :. * . * :* .
gi|29836496|ref|NP_828851.1| NARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAAL 876
gi|30023954|gb|AAP13567.1| NARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAAL 876
gi|476485|pir||JQ2168 EIRDLICVQSYKGIKVLPPLLSENQISGYTLAATSASLFPPWTAAAG--- 979
gi|306156|gb|AAA03055.1| EIRDLICVQSYKGIKVLPPLLSENQISGYTLAATSASLFPPWTAAAG--- 979
gi|549302|sp|P36334|VGL2_CVHOC EIRDLICVQSYKGIKVLPPLLSENQISGYTLAATSASLFPPWTAAAG--- 979
gi|138175|sp|P15423|VGL2_CVH22 SIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAVS--- 766
gi|1869755|emb|CAA71056.1| SIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAVS--- 669
. ** *.* ::*: *** : : :: ** : .. * ...
gi|29836496|ref|NP_828851.1| QIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLT----- 921
gi|30023954|gb|AAP13567.1| QIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLT----- 921
gi|476485|pir||JQ2168 -VPFYLNVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFD----- 1023
gi|306156|gb|AAA03055.1| -VPFYLNVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFD----- 1023
gi|549302|sp|P36334|VGL2_CVHOC -VPFYLNVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFD----- 1023
gi|138175|sp|P15423|VGL2_CVH22 -IPFSLAIQARLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDA 815
gi|1869755|emb|CAA71056.1| -IPFSLAIQARLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDA 718
:** : : *:* :.: :** :*** :* **:*: * :.:
gi|29836496|ref|NP_828851.1| ---------TTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 962
gi|30023954|gb|AAP13567.1| ---------TTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 962
gi|476485|pir||JQ2168 ---------ATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1064
gi|306156|gb|AAA03055.1| ---------ATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1064
gi|549302|sp|P36334|VGL2_CVHOC ---------ATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1064
gi|138175|sp|P15423|VGL2_CVH22 ITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAI 865
gi|1869755|emb|CAA71056.1| ITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAI 768
:. :** *:* *** :.::** * .** ..* ***: :: *
gi|29836496|ref|NP_828851.1| LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS 1012
gi|30023954|gb|AAP13567.1| LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS 1012
gi|476485|pir||JQ2168 LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVN 1114
gi|306156|gb|AAA03055.1| LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVN 1114
gi|549302|sp|P36334|VGL2_CVHOC LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVN 1114
gi|138175|sp|P15423|VGL2_CVH22 YDRLDTIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVN 915
gi|1869755|emb|CAA71056.1| YDRLDTIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVN 818
.*** ::*: *:****.*** :*:.:*:: * : :: * * *:.
gi|29836496|ref|NP_828851.1| ECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPA 1062
gi|30023954|gb|AAP13567.1| ECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPA 1062
gi|476485|pir||JQ2168 ECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTARVSPG 1164
gi|306156|gb|AAA03055.1| ECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTARVSPG 1164
gi|549302|sp|P36334|VGL2_CVHOC ECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTARVSPG 1164
gi|138175|sp|P15423|VGL2_CVH22 ECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSG 965
gi|1869755|emb|CAA71056.1| ECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSG 868
*** .**.* .***:* *::*: : ** *: *:* :*:: . ..
gi|29836496|ref|NP_828851.1| ICHEG-KAYFPREG--VFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCD 1109
gi|30023954|gb|AAP13567.1| ICHEG-KAYFPREG--VFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCD 1109
gi|476485|pir||JQ2168 LCIAGDRGIAPKSG--YFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCA 1212
gi|306156|gb|AAA03055.1| LCIAGDRGIAPKSG--YFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCA 1212
gi|549302|sp|P36334|VGL2_CVHOC LCIAGDRGIAPKSG--YFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCA 1212
gi|138175|sp|P15423|VGL2_CVH22 LCVDGTNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTMADFVQIENCN 1015
gi|1869755|emb|CAA71056.1| LCVDGTNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTMADFVQIENCN 918
:* * .. :. : .. : * : *. * : . .*
gi|29836496|ref|NP_828851.1| VVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVV 1159
gi|30023954|gb|AAP13567.1| VVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVV 1159
gi|476485|pir||JQ2168 VNYTKAPYVMLNTSIPNLPDFKEELDQWFKNQTSVAPDLS-LDYINVTFL 1261
gi|306156|gb|AAA03055.1| VNYTKAPYVMLNTSIPNLPDFKEELDQWFKNQTSVAPDLS-LDYINVTFL 1261
gi|549302|sp|P36334|VGL2_CVHOC VNYTKAPYVMLNTSIPNLPDFKEELDQWFKNQTSVAPDLS-LDYINVTFL 1261
gi|138175|sp|P15423|VGL2_CVH22 VTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLVVEQYNQTIL 1065
gi|1869755|emb|CAA71056.1| VTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLVVEQYNQTIL 968
* :. *: ..:: *:: : .. :. * :.:
gi|29836496|ref|NP_828851.1| NIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQYIKWP 1195
gi|30023954|gb|AAP13567.1| NIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQYIKWP 1195
gi|476485|pir||JQ2168 DLQVEMN--------------RLQEAIKVLNQSYINLKDIGTYEYYVKWP 1297
gi|306156|gb|AAA03055.1| DLQVEMN--------------RLQEAIKVLNQSYINLKDIGTYEYYVKWP 1297
gi|549302|sp|P36334|VGL2_CVHOC DLQVEMN--------------RLQEAIKVLNQSYINLKDIGTYEYYVKWP 1297
gi|138175|sp|P15423|VGL2_CVH22 NLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIKWP 1115
gi|1869755|emb|CAA71056.1| NLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIK-- 1016
:: *:. :*: . :*.: ::*: :. * *:*
gi|29836496|ref|NP_828851.1| WYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEP 1245
gi|30023954|gb|AAP13567.1| WYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEP 1245
gi|476485|pir||JQ2168 WYVWLLICLAGVAMLVLLFFICCCTGCG--TSCFKKCGGCCDDYTGYQEL 1345
gi|306156|gb|AAA03055.1| WYVWLLICLAGVAMLVLLFFICCCTGCG--TSCFKKCGGCCDDYTGYQEL 1345
gi|549302|sp|P36334|VGL2_CVHOC WYVWLLICLAGVAMLVLLFFICCCTGCG--TSCFKKCGGCCDDYTGYQEL 1345
gi|138175|sp|P15423|VGL2_CVH22 WWVWLCISVVLIFVVSMLLLCCCSTGCCGFFSCFASSIRGCCESTKLPYY 1165
gi|1869755|emb|CAA71056.1| --------------------------------------------------
gi|29836496|ref|NP_828851.1| VLKGVKLHYT 1255
gi|30023954|gb|AAP13567.1| VLKGVKLHYT 1255
gi|476485|pir||JQ2168 VIKTSHDD-- 1353
gi|306156|gb|AAA03055.1| VIKTSHDD-- 1353
gi|549302|sp|P36334|VGL2_CVHOC VIKTSHDD-- 1353
gi|138175|sp|P15423|VGL2_CVH22 DVEKIHIQ-- 1173
gi|1869755|emb|CAA71056.1| ----------
----------------- END -----------------